Saturday, July 14, 2012

Gaucher Disease

How Gaucher disease affects Does the body?

Signs and symptoms of Gaucher disease result from the accumulation of Gaucher cells in the body. Gaucher cells generally accumulate in the spleen, liver and bone marrow. They may also accumulate in the lymphatic system, lungs, skin, eyes, kidneys, heart and nervous system.

Gaucher cells in the spleen
Accumulation of Gaucher cells in the spleen causing it to expand (splenomegaly) and hyperactivity. Spleen up to 25 times its normal size and protrude from the abdomen, giving the impression that the person affected is obese or pregnant.

When the spleen becomes overactive, it tends to break down red blood cells faster than they are produced, resulting in a deficiency called anemia. Red blood cells carry oxygen from the lungs to all other body cells. As people with anemia do not have enough red blood cells, they suffer from a lack of oxygen. This is why people with Gaucher disease has affected the spleen may lack energy and endurance.
An overactive spleen may also cause a reduction in the number of platelets (a condition called thrombocytopenia). Decreased platelet count reduces the body's ability to clot blood, which increases the tendency to bleeding and bruising. Therefore, people with Gaucher disease may bleed more frequently and more abundantly from the nose and gums than other people. In women, the rules can also be heavier and last longer.

In addition, hyperactivity of the spleen may cause a decrease in white blood cells in response to excessive filtering. It is normal that the number of white cells in the body fluctuates depending on the presence or absence of invaders. For example, the white blood cell count may increase to fight against bacteria or viruses. However, a decrease in white blood cells due to the presence of Gaucher cells in the spleen may reduce the body's ability to fight infections. People with Gaucher disease are sick more often than others.

Before the enzyme replacement therapy (ERT) is available, people with Gaucher disease often had to undergo removal of their enlarged spleen (an operation called splenectomy). Splenectomized patients, doctors have noted an increased accumulation of Gaucher cells in the liver. Therefore, splenectomy is (usually) longer recommended as a treatment for Gaucher disease.

Gaucher cells in the liver
Gaucher cells can also accumulate in the liver. The liver then increases in volume (a condition called hepatomegaly). Accumulation of Gaucher cells may also lead to cirrhosis, a scarring of the liver or other organ dysfunction. Patients may be predisposed to gallstone formation.

Gaucher cells in bone
For most people with Gaucher disease, the bones are affected. This damage is usually progressive and may become one of the most disabling aspects of the disease.

Accumulation of Gaucher cells in bone marrow can damage bone in several ways. It can reduce blood flow, destroy bone (aseptic necrosis or avascular necrosis) and cause permanent problems of mobility.

Accumulation of Gaucher cells in the bone can also result in decreased bone mass (osteopenia). Minerals (calcium and phosphorus) that act together to maintain the strength and form normal bones lose their effectiveness. Therefore, the bones are prone to infections, they are thinner, more brittle and fracture more easily.

Bone involvement in Gaucher disease can cause areas to appear abnormally hard (sclerosis) along the body of the bone or structural changes such as flattening of the upper femur (thigh bone). For example, if healthy bones are characterized by a rounded shape, a femur affected by Gaucher disease may have a flattened shape at the tip of his head. This condition is called "Erlenmeyer flask deformity" because the bone has a shape similar to a laboratory instrument known as "Erlenmeyer flask". The unusual shape indicates an abnormal formation of new bone (remodeling) because of the presence of Gaucher cells in the marrow.

Learn More type of Bone Disease - causes, symptoms and treatment :
  1. Broken Wrist And Radius
  2. Vertebral Body Fracture, Vertebra
  3. Fractured Neck Of Femur 
  4. Fracture Of The Humerus
  5. Osteoporosis
  6. Broken Collarbone
  7. Plantar Fasciitis Or Heel Spurs
  8. Torn Ligament Of The Ankle Joint Above
  9. Torn Knee Ligaments
  10. Patellar Chondral 
  11. Bone Cancer
  12. Rheumatoid Arthritis
  13. Osteoarthritis
Learn More type of allergy - causes, symptoms and treatment :
  1. Food Allergy  
  2. Latex Allergy
  3. Photodermatitis
  4. Drug Allergy
  5. Hypersensitivity
  6. Alzheimer’s disease

Sunday, June 10, 2012

At what age menopause starts?

It is becoming easier now to know what age menopause begins. Although differences exist from one woman to another, many studies are the beginning of menopause around the age of forty seven years. But it is obvious that this is an average. This means that menopause can begin before or after.
Read more about menopause ;
  • Menopausal Symptoms 
  • Hormonal Changes During Menopause
  • Hormone Replacement Therapy for Menopausal Symptoms
  • Menopause – Other Approaches to Treatment
  • Osteoporosis
  • Menopause in Humans

Friday, April 20, 2012

Symptoms of fever fever deal disease children pharyngitis

Tonsillitis, pharyngitis, the viral and bacterial 
illness fever inflamed throat and tonsils infected with the 
disease is susceptible infants and children. Pharynx is that the periphery of the uvula, with sore throat and cause inflammation, where the tonsils is called tonsillitis and swelling here is that both sides of the throat portion. Pharyngitis as well as fever, but symptoms can be seen, such as runny nose and mild cough cold, do not worry too much because the shallow part of the throat. Tonsillitis is a high fever of around 39 degrees out, but the stronger the sore throat, runny nose symptoms such as cough is not seen much. In the case of viral is a treatable disease if you have to also rest also tonsillitis pharyngitis. For fever and inflammation of the cause, the bacteria but will require treatment using antibiotics. If you do not have a cough and runny nose symptoms such as high fever, even though it was consulted a doctor Let There is also the possibility of pharyngitis and tonsillitis bacterial.
Fever Symptom: Solution: tonsillitis, pharyngitis, in the case of viral symptoms will go like the wind better, if both to rest. Pharyngitis is 2 to 3 days, in the case of tonsillitis has symptoms within one week will be mostly good. The case of bacterial tonsillitis, pharyngitis, however in order to govern the symptoms such as fever and inflammation will require treatment with antibiotics. Pharyngitis and tonsillitis, and streptococcal bacteria such as pneumonia caused by Streptococcus, the bacteria is called pharyngitis, tonsillitis and bacterial (suppurative tonsillitis), respectively. Bacterial tonsillitis tonsils not only inflame, sometimes swollen lymph glands of the neck and chin. Also, if you have a hemolytic streptococcus, can cause rheumatic fever, and acute nephritis after two to three weeks The fever is broken. If Haemophilus influenzae and Streptococcus pneumoniae by, as it can cause bronchitis and pneumonia bacterial Let her see a doctor as soon as possible. At home while the heat has gone out attention to dehydration, always try to replenish the moisture that often.


Symptoms (sinusitis) empyema

Chronic sinusitis, making it easier maxillary sinus is the most fucked.Will be some state is also affected by the other three positions frontal sinus, ethmoid sinus, sphenoid sinus, was inflamed.Symptoms city, stuffy nose, and nasal discharge is top-heavy feeling, smell disorder, previous head. Nasal discharge is purulent mucus mixed with two purulent, or mucous. Two patterns will be the case or around the throat from the hole in the nose. Around towards the throat and nasal discharge, but also may cause coughing or throat clearing.

If symptoms persist nasal discharge, such as stuffy nose, let's seek a specialist in otolaryngology without leave. Also affect nearby organs and to increase in severity is sinusitis. Seems to be also cases, such as otitis media can cause inflammation of the tube from the nose leading to ear, nasal discharge flows into the throat, chronic bronchitis and pharyngitis everywhere, in gastrointestinal disorders.
Empyema ( sinusitis and turn toward the throat by pus accumulated in the sinuses), you may be emitted as bad breath smell of pus. Because the adjacent paranasal sinuses cheek, teeth, and the accumulation of pus in the eyes and sinuses, cheek pain even if symptoms such as pain, toothache, eye occurs would put pressure on the teeth and cheek, and eye there.
Paranasal sinuses, except for one hole of nature, since there is no doorway, easy to spread throughout the inflammation has spread from the nose, pus will be discharged to the outside is difficult. For this reason, there is a peculiar feature of inflammatory paranasal sinus empyema occurred once called stubborn.

Empyema, treatment and prevention of sinusitis

Unlike, such as allergic rhinitis, sinusitis is the treatment of empyema, patience I need. Acute sinusitis, the treatment can be relatively easily, such as oral or injectable antihistamines and antibiotics. Treatment of empyema is the first from macrolide therapy. This will be a long-term drug treatment is administered a small amount of less than half the time taken for the purpose of sterilization of drugs such as antibiotics. Treatment will be held on the prospect for half a year from three months in general. If you do not see the effect of macrolide therapy, so there is more to the surgery.
If improvement is not seen in empyema even after long-term administration of the drug will be conducted the surgery. If time does not have severe symptoms, hospitalization is already in the day surgery without the need in endoscopic surgery. Will be performing surgery in the case of severe root. Surgery will be peeled off the inside of the upper lip, and total excision of the mucosa in the paranasal sinuses. Hospitalization is required because the face is often swollen.
In empyema is sometimes congenital element is affected by the structural characteristics of individuals such as sinusitis and constitution. Has been to prevent sinusitis is difficult because it is full. When people have allergies, nose and throat may be originally weak. You must train the body with moderate exercise, unbalanced diet to avoid attention to nutrition, boost the immune system of the body. Strive for that life style that does not burden enforcement of hand washing and gargling, and to clean living environment, the nose is important.

Cause of the empyema

Of chronic sinusitis due to many factors, such as hypertrophic rhinitis and allergic mucosa thick jam made ​​repeatedly, genetic constitution, of acute inflammation of the nose is complex and are related.
Many causes of cough and fever lasts more than a week in infants, wheezing, and nasal discharge, there seems to be sinusitis. The case of infants, many of the symptoms if symptoms are not typical, difficult to distinguish from common cold and fever, cough, and wheezing, it is likely to be diagnosed with it, such as colds and rhinitis.


Thursday, April 19, 2012

streptococcal pharyngitis

Many cases be a sign of throat pain is suffering from ill will, see a doctor because it hurts, there are many very throat. I get sore throat by influenza and colds, such as, in many cases, virus infection, will be better a few days. 

There is a streptococcal pharyngitis is sore throat to cause a small number. Streptococcal pharyngitis is caused by bacterial infection that is almost the case. Throat and it hurts the cause of the other, unlike that streptococcal pharyngitis is treated is possible. Against bacteria is the cause of strep throat with antibiotics is very effective, you can also reduce by the use of antibiotics, the infection to other people to. 

Streptococcal pharyngitis and left alone without treatment, it may cause complications such as rheumatic fever. Rheumatic fever can cause terrible joint pain, severe cases and damage to the heart.There is also a potential nephritis as a complication of other also. 

Streptococcal pharyngitis is seen many 15-year-old children from the age of five, there are likely to develop in all age groups. The sore throat may be signs of symptoms such as fever and swollen lymph glands. The child may also complain when the ordinary.

Tuesday, April 17, 2012

Strep Throat Symptoms

Strep throat is a bacterial infection caused by Streptococcus pyogenes (strep) bacteria group. You can see more adults than children, but adults sometimes do not get. The flu season is out of the tournament can be the worst strep throat.
The virus responsible for causing a sore throat is very contagious. Especially in flu season, it is very difficult to prevent this from occurring, sore throat. Decrease the chances of contracting the virus that causes sore throat for better personal hygiene, but can not completely prevent infection. Responsible for the spread of viruses in the air cause sore throat, secretions or direct contact.
Antibiotics for strep throat can also be effective in preventing the occurrence of various diseases, the most commonly prescribed medications are not always fully streptococcus bacterial infection can not be overcome. This type of common bacteria to antibiotics and prescribing an effective treatment for strep throat doctors these days has become very resistant to experience problems.
Sore throat is usually the result of a chill. Milk, and milk products are harmful to a state.Take a spoonful of honey with lukewarm water glass in the morning and before sleep at night. Apply a cool compress the throat and a wool cloth to compress protection. Only a week to take the bread, vegetables and fruits.
Aching back and sore throat have been a feature of your throat. This is a regular normal conditions. That he would be any more pleasant. Oftentimes, the first symptoms of a sore throat for a our bodys' fight against the common cold or flu. Many of the people, soothe a sore throat, it is best to drink a cup of hot tea with honey.
belleric myrobalan, commonly known as Ayurveda behera practice, coughs popular solution to the Indian home. Taken from the fruit pulp. The flesh is mixed with salt, long pepper and honey. The sore throat problems, allaying for granted. Instead, the preparation, it was covered with wheat flour and then fried fruit can be roasted on a low flame.
Natural health remedies for sore throat is gargling has been made known. Gargling with salt or a mixture of soft and warm water, 4-6 drops of grapefruit seed extract, sage or raspberry leaf tea or other herbal teas, several times a day, the sore throat pain relief, reduce inflammation and hydrate dry tissue.
To less than a ginger root extract, the addition of 1/3 cup boiling water and sugar in a tablespoon. This is when I drink a little bit wet. One of the most well liked sore throat home remedies for a
If you have a cold or a sore throat followed by fever, such as echinacea and goldenseal or Oregon grape root herbal enhancers of the immune system effectively. A wonderful herb, garlic, illness, one can also prove helpful, it is harmufl bacteria, virus, because it is running. Try to add raw garlic to your salads and other dishes.
Salt and pepper Salt and pepper limbu absorbs it and press a spoon spatula or the back cover with a half lemon. Warm oven or microwave either lemon. Do not temperature. Then the hot, slow lick of lemon, there is no juice, as well as squeezing in time. The Repeat 2 to 3 times.